Hope Waisner, Ph.D. is a research analyst with extensive experience in biomedical science research in the fields of virology, microbiology, cell biology, molecular genetics, and immunology. Her work involves analyzing medical records and related literature, as well as providing medical analyses and summaries for fact investigation and discovery. She also focuses on analyzing and summarizing scientific research articles on various diverse topics, providing data and support for regulatory matters. She has assisted with the preparation and development of submissions addressing issues raised as a result of Food and Drug Administration regulations.
Hope has authored numerous scientific publications, presented her work at national and international scientific conferences, and is the recipient of the Karen and Kelly Gregg Award for Excellence in Infectious Disease Research.
Peer-reviewed journals in which Hope's work appears include:
mBio
Journal of Virology
Frontiers in Cell and Developmental Biology
Microbiology Spectrum
Retrovirology
Viruses
Highlighted Publications
Dogrammatzis C*, Saud R*, Waisner H*, Lasnier S, Suma SM, Grieshaber B, Kalamvoki M. Tracing the STING exocytosis pathway during herpes viruses infection. mBio. 2024 Mar 12:e0037324. doi: 10.1128/mbio.00373-24.
Waisner H*, Lasnier S*, Muraleedharan Suma S, Kalamvoki M. Effects on exocytosis by two HSV-1 mutants unable to block autophagy. J Virol. 2023 Sep 15;e00757-23. doi: 10.1128/JVI.00757-23.
Waisner H, Grieshaber B, Saud R, Henke W, Stephens EB, Kalamvoki M. SARS-CoV-2 Harnesses Host Translational Shutoff and Autophagy To Optimize Virus Yields: the Role of the Envelope (E) Protein. Microbiol Spectr. 2023 Feb 14;11(1):e0370722. doi: 10.1128/spectrum.03707-22.
Henke W, Waisner H, Arachchige SP, Kalamvoki M, Stephens E. The envelope proteins from SARS-CoV-2 and SARS-CoV potently reduce the infectivity of human immunodeficiency virus type 1 (HIV-1). Retrovirology. 2022 Nov 19;19(1):25. doi: 10.1186/s12977-022-00611-6.
Dogrammatzis C*, Waisner H*, Kalamvoki M. "Non-Essential" Proteins of HSV-1 with Essential Roles In Vivo: A Comprehensive Review. Viruses. 2020 Dec 23;13(1):17. doi: 10.3390/v13010017.
Dogrammatzis C*, Waisner H*, Kalamvoki M. Cloaked Viruses and Viral Factors in Cutting Edge Exosome-Based Therapies. Front Cell Dev Biol. 2020 May 26;8:376. doi: 10.3389/fcell.2020.00376.
Waisner H, Kalamvoki M. The ICP0 Protein of Herpes Simplex Virus 1 (HSV-1) Downregulates Major Autophagy Adaptor Proteins Sequestosome 1 and Optineurin during the Early Stages of HSV-1 Infection. J Virol. 2019 Oct 15;93(21):e01258-19. doi: 10.1128/JVI.01258-19.
Deschamps T, Waisner H, Dogrammatzis C, Roy A, Chacko S, Perera C, Prisinzano TE, Kalamvoki M. Discovery of Small-Molecule Inhibitors Targeting the E3 Ubiquitin Ligase Activity of the Herpes Simplex Virus 1 ICP0 Protein Using an In Vitro High-Throughput Screening Assay. J Virol. 2019 Jun 14;93(13):e00619-19. doi: 10.1128/JVI.00619-19.
Previous Experience
Postdoctoral Fellow, University of Kansas Medical Center